Mitochondrial Dysfunction in Aging and Diseases of Aging

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Title

Mitochondrial Dysfunction in Aging and Diseases of Aging

Subject

Biology

Description

This collection of review articles authored by international experts pulls together current
information about the role of mitochondria in aging and diseases of aging. Mitochondria
are vitally important cellular organelles and undergo their own aging process becoming
less efficient in aged animals including humans. These changes have wide-ranging
significance contributing to immune dysfunction (autoimmunity and immune deficiency),
inflammation, delayed healing, skin and retinal damage, cancer and most of the
degenerative diseases of aging. Mitochondrial aging predisposes to drug toxicity in the
geriatric population and to many of the features of normal aging. The research detailed
in this book summarizes current understanding of the role of mitochondria in the
complex molecular changes of aging, moving on to specific diseases of aging.
Mitochondrial dysfunction is an important target for development of treatments for aging
and disease. The last article details how exercise is a treatment and combats many
features of the aging process.

Creator

Richard H. Haas
(Ed.)

Source

mdpi.com/books/pdfview/book/1606

Publisher

MDPI AG
St. Alban-Anlage 66
4052 Basel, Switzerland
Tel: +41 61 683 77 34
www.mdpi.com/books
[email protected]

Date

September 2019

Contributor

J®F

Rights

CC BY-NC-ND licence

Format

Pdf

Language

English

Type

Textbook

Identifier

ISBN 978-3-03921-327-6 (Pbk)
ISBN 978-3-03921-328-3 (PDF)

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