Steroid Compounds with Potential Biological Activity

Steroid Compounds with Potential Biological Activity

Molecules

Steroids are a large group of compounds whose structure is based on a 17-carbon skeleton, with a specific cyclopentanoperhydrophenanthrene ring system. Natural steroids have been fine-tuned through evolution to build membranes; act as chemical messengers that regulate metabolic, immune and reproductive functions in animals and stimulate the growth of, or otherwise protect, animal organisms. The steroid core represents a suitable motive for structural modifications. Therefore, a large group of semi-synthetic steroid derivatives have occupied the attention of synthetic chemists as well as medicinal chemists due to their potential biological activity, including anticancer, antibacterial, anti-inflammatory and (anti)hormonal activities. This Reprint of the Special Issue ofMolecules titled “Steroid Compounds with Potential Biological Activity” is dedicated to both experimental and theoretical studies on steroid chemistry, structural biology, biosynthesis, metabolism, and pharmacology. The Issue focuses on the isolation and synthesis of steroid compounds, diverse in origin, as well as their structural characterization and identification. Published articles and reviews relate to in vitro and in silico studies of the pharmacological properties, molecular biology, biochemistry and structural biology of steroids.

Marina Savi´c (Ed) Erzs ´ebet Merny´ak (Ed) Jovana Ajdukovic (Ed) Suzana Jovanovi´c-Santa (Ed)

www.mdpi.com/journal/molecules/special issues/ Steroid Compounds Biological Activity

MDPI St. Alban-Anlage 66 4052 Basel, Switzerland

2023

J®F

The book as a whole is distributed by MDPI under the terms and conditions of the Creative Commons Attribution-NonCommercial-NoDerivs (CC BY-NC-ND) license.

Pdf

English

Textbooks

ISBN 978-3-0365-9617-4 (Hbk) ISBN 978-3-0365-9616-7 (PDF) doi.org/10.3390/books978-3-0365-9616-7