Dublin Core
Title
Solving the Puzzle: Molecular Research in Inflammatory Bowel Diseases
Subject
Molecular Sciences
Description
Inflammatory bowel disease (IBD) encompasses chronic idiopathic relapsing and
remitting gastrointestinal autoimmune diseases characterized by chronic inflammatory
disorders of complex etiology, posing clinical challenges due to their o6en therapyrefractory nature. The primary disorders within the IBD classification are ulcerative colitis
(UC) and Crohn’s disease (CD), sharing similarities but exhibiting distinct differences,
sometimes making their discrimination challenging.
A prominent feature of IBD is the inflammation of the intestinal mucosa, characterized by
the robust and persistent infiltration of immune cells and compromised intestinal barrier
integrity, leading to a phenomenon known as “leaky gut.” Inflammation can manifest
acutely or chronically, known as relapsing, and can increase in severity over time, thereby
causing life-long morbidities and reduced quality of life for affected individuals,
underscoring the need for a deeper comprehension of the molecular contributors to
disease pathogenesis and progression.
Creator
Susanne M. Krug (Ed.)
Source
www.mdpi.com/journal/
ijms/special issues/IBDs
Publisher
MDPI
St. Alban-Anlage 66
4052 Basel, Switzerland
Date
2023
Contributor
J®F
Rights
The book as a whole is distributed by MDPI under the terms
and conditions of the Creative Commons Attribution-NonCommercial-NoDerivs (CC BY-NC-ND)
license.
Format
Pdf
Language
English
Type
Textbooks
Identifier
ISBN 978-3-0365-9864-2 (Hbk)
ISBN 978-3-0365-9863-5 (PDF)
doi.org/10.3390/books978-3-0365-9863-5